ВЗАИМОСВЯЗЬ ЭНДОКАННАБИНОИДНОЙ СИСТЕМЫ И ФИЗИЧЕСКОЙ АКТИВНОСТИ
Ключевые слова:
эндоканнабиноидная система, физическая активность, нейротрансмиттеры, синаптическая передача
Аннотация
Цель: обобщение результатов исследований и выявление взаимосвязей эндоканнабиноидной системы с физической активностью человека. Материалы и методы. Исследованы доктринальные источники, для определения взаимодействия эндоканнабиноидной системы на организм человека во время физической активности, а также проанализирована данная информация. Результаты. Инициированные серии цепных реакций эндоканнабиноидной системы, которые регулируют и контролируют все клеточные процессы и последующие биологические эффекты, играют важную роль в балансировании возбудимости круговых путей, контролирующих двигательные действия. Заключение. Эндоканнабиноидная система играет важную роль в балансировании возбудимости круговых цепей, контролирующих двигательные акты, действующие на физиологический ответ организма – физические упражнения.
Литература
1. Караман Ю.К., Лобанова Е.Г. Эндоканнабиноиды и эйкозаноиды: биосинтез, механизмы их взаимосвязи, роль в иммунных процессах // Мед. иммунология. 2013. Т. 15, № 2. С. 119–130. [Karaman Yu.K., Lobanova E.G. [Endocannabinoids and Eicosamoids. Biosynthesis, Mecпhanisms of Their Relationship, Role in Immune Processes]. Meditsinskaya immunologiya [Medical Immunology], 2013, vol. 15, no. 2, pp. 119–130. (in Russ.)] DOI: 10.15789/1563-0625-2013-2-119-130
2. Кытикова О.Ю., Антонюк М.В., Гвозденко Т.А. Метаболические аспекты взаимосвязи ожирения и бронхиальной астмы // Ожирение и метаболизм. 2018. Т. 15, № 4. С. 9−14. [Kytikova O.Yu., Antonyuk M.V., Gvozdenko T.A. [Metabolic Aspects of the Relationship Between Obesity and Bronchial Asthma]. Ozhirenie i metabolism [Obesity and Metabolism], 2018, vol. 15, no. 4, pp. 9−14. (in Russ.)] DOI: 10.14341/omet9578
3. Хаспеков Л.Г., Бобров М.Ю. Эндогенная каннабиноидная система и ее защитная роль при ишемическом и цитотоксическом повреждении нейронов головного мозга // Нейрохимия. 2006. Т. 23, № 2. C. 85–105. [Khaspekov L.G., Bobrov M.Yu. [Endogenous Cannabinoid System and its Protective Role in Ischemic and Cytotoxic Damage to Brain Neurons]. Neyrokhimiya [Neurochemistry], 2006, vol. 23, no. 2, pp. 85–105. (in Russ.)]
4. Шубина Л.В., Кичигина В.Ф. Эндогенная каннабиноидная система мозга: роль в регуляции судорожной активности // Успехи физиол. наук. 2012. Т. 43, № 3. С. 21–37. [Shubina L.V., Kichigina V.F. [The Endogenous Cannabinoid System of the Brain. A Role in the Regulation of Seizure Activity]. Uspekhi fiziologicheskikh nauk [Advances in Physiological Sciences], 2012, vol. 43, no. 3, pp. 21–37. (in Russ.)]
5. Di Marzo V., De Petrocellis L., Fezza F. et al. Anandamide Receptors. Prostaglandins, Leukotrienes and Essential Fatty Acids, 2002, vol. 66, pp. 377–391. DOI: 10.1054/plef.2001.0349
6. Fernández-Ruiz J., Romero J., Velasco G. et al. Cannabinoid CB2 Receptor. A New Target for Controlling Neural Cell Survival. Trends in Pharmacological Sciences, vol. 28, pp. 39–45. DOI: 10.1016/j.tips.2006.11.001
7. Callén L., Moreno E., Barraso-Chinea P. et al. Cannabinoid Receptors CB1 and CB2 Form Functional Heteromers in the Brain. Journal of Biological Chemistry, 2012, vol. 287, pp. 20851–20865. DOI: 10.1074/jbc.M111.335273
8. Dubreucq S., Koehl M., Abrous D.N. et al. CB1 Receptor Deficiency Decreases Wheel-running Activity: Consequences on Emotional Behaviours and Hippocampal Neurogenesis. Experimental Neurology, 2010, vol. 224, pp. 106–113. DOI: 10.1016/j.expneurol.2010.01.017
9. Cota D. CB1 Receptors: Emerging Evidence for Central and Peripheral Mechanisms That Regulate Energy Balance, Metabolism, and Cardiovascular Health. Diabetes/Metabolism Research and Reviews, 2007, vol. 23, pp. 507–517. DOI: 10.1002/dmrr.764
10. Dietrich A., McDaniel W.F. Endocannabinoids and Exercise. British Journal of Sports Medicine, 2004, vol. 38, pp. 536–541. DOI: 10.1136/bjsm.2004.011718
11. El Manira A., Kyriakatos A. The Role of Endocannabinoid Signaling in Motor Control. Physiology, 2010, vol. 25, no. 4, pp. 230–233. DOI: 10.1152/physiol.00007.2010
12. Sparling P.B., Giuffrida A., Piomelli D. et al. Exercise Activates the Endocannabinoid System. NeuroReport, 2003, vol. 14, no. 17, pp. 2209–2211. DOI: 10.1097/00001756-200312020-00015
13. Antunes H.K., Leite G.S., Lee K.S. et al. Exercise Deprivation Increases Negative Mood in Exercise-addicted Subjects and Modifies Their Biochemical Markers. Physiology & Behavior, 2016, vol. 156, pp. 182–190. DOI: 10.1016/j.physbeh.2016.01.028
14. Raichlen D.A., Foster A.D., Seillier A. et al. Exercise-induced Endocannabinoid Signaling is Modulated by Intensity. European Journal of Applied Physiology, 2013, vol. 113, no. 4, pp. 869–875. DOI: 10.1007/s00421-012-2495-5
15. Gleeson M., Walsh N.P., British Association of Sport and Exercise Sciences. The BASES Expert Statement on Exercise, Immunity, and Infection. Journal of Sports Science, 2012, vol. 30, no. 3, pp. 321–324. DOI: 10.1080/02640414.2011.627371
16. Hamedinia M., Sharifi M., Hosseini-Kakhak A. The Effect of Eight Weeks of Aerobic, Anaerobic and Resistance Training on Some Factor of Endocannabinoid System, Serotonin, Beta-Endorphin and BDNF in Young Men. Biosciences Biotechnology Research Asia, 2017, vol. 14, no. 3, pp. 1201–1210. DOI: 10.13005/bbra/2562
17. Lu HC., Mackie K. An Introduction to the Endogenous Cannabinoid System. Biological Psychiatry, 2016, vol. 79, no. 7, pp. 516–525. DOI: 10.1016/j.biopsych.2015.07.028
18. Maccarrone M., Fiori A., Bari M. et al. Regulation by Cannabinoid Receptors of Anandamide Transport Across the Blood-brain Barrier and Through Other Endothelial Cells. Throm-bosis and Haemostasis, 2006, vol. 95, no. 1, pp. 117–127. DOI: 10.1160/TH05-06-0413
19. Viscomi M.T., Oddi S., Latini L. et al. Selective CB2 Receptor Agonism Protects Central Neurons from Remote Axotomy-induced Apoptosis Through the PI3K/Akt Pathway. Journal of Neuroscience, 2009, no. 29, pp. 4564–4570. DOI: 10.1523/JNEUROSCI.0786-09.2009
20. Cavuoto P., McAinch A.J., Hatzinikolas G. et al. The Expression of Receptors for Endo-cannabinoids in Human and Rodentskeletal Muscle. Biochemical and Biophysical Research, 2007, vol. 364, pp. 105–111. DOI: 10.1016/j.bbrc.2007.09.099
21. Gasperi V., Ceci R., Tantimonaco M. et al. The Fatty Acid Amide Hydrolase in Lympho-cytes from Sedentary and Active Subjects. Medicine & Science in Sports & Exercise, 2014, vol. 1 (46), pp. 24–32. DOI: 10.1249/MSS.0b013e3182a10ce6
2. Кытикова О.Ю., Антонюк М.В., Гвозденко Т.А. Метаболические аспекты взаимосвязи ожирения и бронхиальной астмы // Ожирение и метаболизм. 2018. Т. 15, № 4. С. 9−14. [Kytikova O.Yu., Antonyuk M.V., Gvozdenko T.A. [Metabolic Aspects of the Relationship Between Obesity and Bronchial Asthma]. Ozhirenie i metabolism [Obesity and Metabolism], 2018, vol. 15, no. 4, pp. 9−14. (in Russ.)] DOI: 10.14341/omet9578
3. Хаспеков Л.Г., Бобров М.Ю. Эндогенная каннабиноидная система и ее защитная роль при ишемическом и цитотоксическом повреждении нейронов головного мозга // Нейрохимия. 2006. Т. 23, № 2. C. 85–105. [Khaspekov L.G., Bobrov M.Yu. [Endogenous Cannabinoid System and its Protective Role in Ischemic and Cytotoxic Damage to Brain Neurons]. Neyrokhimiya [Neurochemistry], 2006, vol. 23, no. 2, pp. 85–105. (in Russ.)]
4. Шубина Л.В., Кичигина В.Ф. Эндогенная каннабиноидная система мозга: роль в регуляции судорожной активности // Успехи физиол. наук. 2012. Т. 43, № 3. С. 21–37. [Shubina L.V., Kichigina V.F. [The Endogenous Cannabinoid System of the Brain. A Role in the Regulation of Seizure Activity]. Uspekhi fiziologicheskikh nauk [Advances in Physiological Sciences], 2012, vol. 43, no. 3, pp. 21–37. (in Russ.)]
5. Di Marzo V., De Petrocellis L., Fezza F. et al. Anandamide Receptors. Prostaglandins, Leukotrienes and Essential Fatty Acids, 2002, vol. 66, pp. 377–391. DOI: 10.1054/plef.2001.0349
6. Fernández-Ruiz J., Romero J., Velasco G. et al. Cannabinoid CB2 Receptor. A New Target for Controlling Neural Cell Survival. Trends in Pharmacological Sciences, vol. 28, pp. 39–45. DOI: 10.1016/j.tips.2006.11.001
7. Callén L., Moreno E., Barraso-Chinea P. et al. Cannabinoid Receptors CB1 and CB2 Form Functional Heteromers in the Brain. Journal of Biological Chemistry, 2012, vol. 287, pp. 20851–20865. DOI: 10.1074/jbc.M111.335273
8. Dubreucq S., Koehl M., Abrous D.N. et al. CB1 Receptor Deficiency Decreases Wheel-running Activity: Consequences on Emotional Behaviours and Hippocampal Neurogenesis. Experimental Neurology, 2010, vol. 224, pp. 106–113. DOI: 10.1016/j.expneurol.2010.01.017
9. Cota D. CB1 Receptors: Emerging Evidence for Central and Peripheral Mechanisms That Regulate Energy Balance, Metabolism, and Cardiovascular Health. Diabetes/Metabolism Research and Reviews, 2007, vol. 23, pp. 507–517. DOI: 10.1002/dmrr.764
10. Dietrich A., McDaniel W.F. Endocannabinoids and Exercise. British Journal of Sports Medicine, 2004, vol. 38, pp. 536–541. DOI: 10.1136/bjsm.2004.011718
11. El Manira A., Kyriakatos A. The Role of Endocannabinoid Signaling in Motor Control. Physiology, 2010, vol. 25, no. 4, pp. 230–233. DOI: 10.1152/physiol.00007.2010
12. Sparling P.B., Giuffrida A., Piomelli D. et al. Exercise Activates the Endocannabinoid System. NeuroReport, 2003, vol. 14, no. 17, pp. 2209–2211. DOI: 10.1097/00001756-200312020-00015
13. Antunes H.K., Leite G.S., Lee K.S. et al. Exercise Deprivation Increases Negative Mood in Exercise-addicted Subjects and Modifies Their Biochemical Markers. Physiology & Behavior, 2016, vol. 156, pp. 182–190. DOI: 10.1016/j.physbeh.2016.01.028
14. Raichlen D.A., Foster A.D., Seillier A. et al. Exercise-induced Endocannabinoid Signaling is Modulated by Intensity. European Journal of Applied Physiology, 2013, vol. 113, no. 4, pp. 869–875. DOI: 10.1007/s00421-012-2495-5
15. Gleeson M., Walsh N.P., British Association of Sport and Exercise Sciences. The BASES Expert Statement on Exercise, Immunity, and Infection. Journal of Sports Science, 2012, vol. 30, no. 3, pp. 321–324. DOI: 10.1080/02640414.2011.627371
16. Hamedinia M., Sharifi M., Hosseini-Kakhak A. The Effect of Eight Weeks of Aerobic, Anaerobic and Resistance Training on Some Factor of Endocannabinoid System, Serotonin, Beta-Endorphin and BDNF in Young Men. Biosciences Biotechnology Research Asia, 2017, vol. 14, no. 3, pp. 1201–1210. DOI: 10.13005/bbra/2562
17. Lu HC., Mackie K. An Introduction to the Endogenous Cannabinoid System. Biological Psychiatry, 2016, vol. 79, no. 7, pp. 516–525. DOI: 10.1016/j.biopsych.2015.07.028
18. Maccarrone M., Fiori A., Bari M. et al. Regulation by Cannabinoid Receptors of Anandamide Transport Across the Blood-brain Barrier and Through Other Endothelial Cells. Throm-bosis and Haemostasis, 2006, vol. 95, no. 1, pp. 117–127. DOI: 10.1160/TH05-06-0413
19. Viscomi M.T., Oddi S., Latini L. et al. Selective CB2 Receptor Agonism Protects Central Neurons from Remote Axotomy-induced Apoptosis Through the PI3K/Akt Pathway. Journal of Neuroscience, 2009, no. 29, pp. 4564–4570. DOI: 10.1523/JNEUROSCI.0786-09.2009
20. Cavuoto P., McAinch A.J., Hatzinikolas G. et al. The Expression of Receptors for Endo-cannabinoids in Human and Rodentskeletal Muscle. Biochemical and Biophysical Research, 2007, vol. 364, pp. 105–111. DOI: 10.1016/j.bbrc.2007.09.099
21. Gasperi V., Ceci R., Tantimonaco M. et al. The Fatty Acid Amide Hydrolase in Lympho-cytes from Sedentary and Active Subjects. Medicine & Science in Sports & Exercise, 2014, vol. 1 (46), pp. 24–32. DOI: 10.1249/MSS.0b013e3182a10ce6
2. Кытикова О.Ю., Антонюк М.В., Гвозденко Т.А. Метаболические аспекты взаимосвязи ожирения и бронхиальной астмы // Ожирение и метаболизм. 2018. Т. 15, № 4. С. 9−14. [Kytikova O.Yu., Antonyuk M.V., Gvozdenko T.A. [Metabolic Aspects of the Relationship Between Obesity and Bronchial Asthma]. Ozhirenie i metabolism [Obesity and Metabolism], 2018, vol. 15, no. 4, pp. 9−14. (in Russ.)] DOI: 10.14341/omet9578
3. Хаспеков Л.Г., Бобров М.Ю. Эндогенная каннабиноидная система и ее защитная роль при ишемическом и цитотоксическом повреждении нейронов головного мозга // Нейрохимия. 2006. Т. 23, № 2. C. 85–105. [Khaspekov L.G., Bobrov M.Yu. [Endogenous Cannabinoid System and its Protective Role in Ischemic and Cytotoxic Damage to Brain Neurons]. Neyrokhimiya [Neurochemistry], 2006, vol. 23, no. 2, pp. 85–105. (in Russ.)]
4. Шубина Л.В., Кичигина В.Ф. Эндогенная каннабиноидная система мозга: роль в регуляции судорожной активности // Успехи физиол. наук. 2012. Т. 43, № 3. С. 21–37. [Shubina L.V., Kichigina V.F. [The Endogenous Cannabinoid System of the Brain. A Role in the Regulation of Seizure Activity]. Uspekhi fiziologicheskikh nauk [Advances in Physiological Sciences], 2012, vol. 43, no. 3, pp. 21–37. (in Russ.)]
5. Di Marzo V., De Petrocellis L., Fezza F. et al. Anandamide Receptors. Prostaglandins, Leukotrienes and Essential Fatty Acids, 2002, vol. 66, pp. 377–391. DOI: 10.1054/plef.2001.0349
6. Fernández-Ruiz J., Romero J., Velasco G. et al. Cannabinoid CB2 Receptor. A New Target for Controlling Neural Cell Survival. Trends in Pharmacological Sciences, vol. 28, pp. 39–45. DOI: 10.1016/j.tips.2006.11.001
7. Callén L., Moreno E., Barraso-Chinea P. et al. Cannabinoid Receptors CB1 and CB2 Form Functional Heteromers in the Brain. Journal of Biological Chemistry, 2012, vol. 287, pp. 20851–20865. DOI: 10.1074/jbc.M111.335273
8. Dubreucq S., Koehl M., Abrous D.N. et al. CB1 Receptor Deficiency Decreases Wheel-running Activity: Consequences on Emotional Behaviours and Hippocampal Neurogenesis. Experimental Neurology, 2010, vol. 224, pp. 106–113. DOI: 10.1016/j.expneurol.2010.01.017
9. Cota D. CB1 Receptors: Emerging Evidence for Central and Peripheral Mechanisms That Regulate Energy Balance, Metabolism, and Cardiovascular Health. Diabetes/Metabolism Research and Reviews, 2007, vol. 23, pp. 507–517. DOI: 10.1002/dmrr.764
10. Dietrich A., McDaniel W.F. Endocannabinoids and Exercise. British Journal of Sports Medicine, 2004, vol. 38, pp. 536–541. DOI: 10.1136/bjsm.2004.011718
11. El Manira A., Kyriakatos A. The Role of Endocannabinoid Signaling in Motor Control. Physiology, 2010, vol. 25, no. 4, pp. 230–233. DOI: 10.1152/physiol.00007.2010
12. Sparling P.B., Giuffrida A., Piomelli D. et al. Exercise Activates the Endocannabinoid System. NeuroReport, 2003, vol. 14, no. 17, pp. 2209–2211. DOI: 10.1097/00001756-200312020-00015
13. Antunes H.K., Leite G.S., Lee K.S. et al. Exercise Deprivation Increases Negative Mood in Exercise-addicted Subjects and Modifies Their Biochemical Markers. Physiology & Behavior, 2016, vol. 156, pp. 182–190. DOI: 10.1016/j.physbeh.2016.01.028
14. Raichlen D.A., Foster A.D., Seillier A. et al. Exercise-induced Endocannabinoid Signaling is Modulated by Intensity. European Journal of Applied Physiology, 2013, vol. 113, no. 4, pp. 869–875. DOI: 10.1007/s00421-012-2495-5
15. Gleeson M., Walsh N.P., British Association of Sport and Exercise Sciences. The BASES Expert Statement on Exercise, Immunity, and Infection. Journal of Sports Science, 2012, vol. 30, no. 3, pp. 321–324. DOI: 10.1080/02640414.2011.627371
16. Hamedinia M., Sharifi M., Hosseini-Kakhak A. The Effect of Eight Weeks of Aerobic, Anaerobic and Resistance Training on Some Factor of Endocannabinoid System, Serotonin, Beta-Endorphin and BDNF in Young Men. Biosciences Biotechnology Research Asia, 2017, vol. 14, no. 3, pp. 1201–1210. DOI: 10.13005/bbra/2562
17. Lu HC., Mackie K. An Introduction to the Endogenous Cannabinoid System. Biological Psychiatry, 2016, vol. 79, no. 7, pp. 516–525. DOI: 10.1016/j.biopsych.2015.07.028
18. Maccarrone M., Fiori A., Bari M. et al. Regulation by Cannabinoid Receptors of Anandamide Transport Across the Blood-brain Barrier and Through Other Endothelial Cells. Throm-bosis and Haemostasis, 2006, vol. 95, no. 1, pp. 117–127. DOI: 10.1160/TH05-06-0413
19. Viscomi M.T., Oddi S., Latini L. et al. Selective CB2 Receptor Agonism Protects Central Neurons from Remote Axotomy-induced Apoptosis Through the PI3K/Akt Pathway. Journal of Neuroscience, 2009, no. 29, pp. 4564–4570. DOI: 10.1523/JNEUROSCI.0786-09.2009
20. Cavuoto P., McAinch A.J., Hatzinikolas G. et al. The Expression of Receptors for Endo-cannabinoids in Human and Rodentskeletal Muscle. Biochemical and Biophysical Research, 2007, vol. 364, pp. 105–111. DOI: 10.1016/j.bbrc.2007.09.099
21. Gasperi V., Ceci R., Tantimonaco M. et al. The Fatty Acid Amide Hydrolase in Lympho-cytes from Sedentary and Active Subjects. Medicine & Science in Sports & Exercise, 2014, vol. 1 (46), pp. 24–32. DOI: 10.1249/MSS.0b013e3182a10ce6
References
1. Караман Ю.К., Лобанова Е.Г. Эндоканнабиноиды и эйкозаноиды: биосинтез, механизмы их взаимосвязи, роль в иммунных процессах // Мед. иммунология. 2013. Т. 15, № 2. С. 119–130. [Karaman Yu.K., Lobanova E.G. [Endocannabinoids and Eicosamoids. Biosynthesis, Mecпhanisms of Their Relationship, Role in Immune Processes]. Meditsinskaya immunologiya [Medical Immunology], 2013, vol. 15, no. 2, pp. 119–130. (in Russ.)] DOI: 10.15789/1563-0625-2013-2-119-1302. Кытикова О.Ю., Антонюк М.В., Гвозденко Т.А. Метаболические аспекты взаимосвязи ожирения и бронхиальной астмы // Ожирение и метаболизм. 2018. Т. 15, № 4. С. 9−14. [Kytikova O.Yu., Antonyuk M.V., Gvozdenko T.A. [Metabolic Aspects of the Relationship Between Obesity and Bronchial Asthma]. Ozhirenie i metabolism [Obesity and Metabolism], 2018, vol. 15, no. 4, pp. 9−14. (in Russ.)] DOI: 10.14341/omet9578
3. Хаспеков Л.Г., Бобров М.Ю. Эндогенная каннабиноидная система и ее защитная роль при ишемическом и цитотоксическом повреждении нейронов головного мозга // Нейрохимия. 2006. Т. 23, № 2. C. 85–105. [Khaspekov L.G., Bobrov M.Yu. [Endogenous Cannabinoid System and its Protective Role in Ischemic and Cytotoxic Damage to Brain Neurons]. Neyrokhimiya [Neurochemistry], 2006, vol. 23, no. 2, pp. 85–105. (in Russ.)]
4. Шубина Л.В., Кичигина В.Ф. Эндогенная каннабиноидная система мозга: роль в регуляции судорожной активности // Успехи физиол. наук. 2012. Т. 43, № 3. С. 21–37. [Shubina L.V., Kichigina V.F. [The Endogenous Cannabinoid System of the Brain. A Role in the Regulation of Seizure Activity]. Uspekhi fiziologicheskikh nauk [Advances in Physiological Sciences], 2012, vol. 43, no. 3, pp. 21–37. (in Russ.)]
5. Di Marzo V., De Petrocellis L., Fezza F. et al. Anandamide Receptors. Prostaglandins, Leukotrienes and Essential Fatty Acids, 2002, vol. 66, pp. 377–391. DOI: 10.1054/plef.2001.0349
6. Fernández-Ruiz J., Romero J., Velasco G. et al. Cannabinoid CB2 Receptor. A New Target for Controlling Neural Cell Survival. Trends in Pharmacological Sciences, vol. 28, pp. 39–45. DOI: 10.1016/j.tips.2006.11.001
7. Callén L., Moreno E., Barraso-Chinea P. et al. Cannabinoid Receptors CB1 and CB2 Form Functional Heteromers in the Brain. Journal of Biological Chemistry, 2012, vol. 287, pp. 20851–20865. DOI: 10.1074/jbc.M111.335273
8. Dubreucq S., Koehl M., Abrous D.N. et al. CB1 Receptor Deficiency Decreases Wheel-running Activity: Consequences on Emotional Behaviours and Hippocampal Neurogenesis. Experimental Neurology, 2010, vol. 224, pp. 106–113. DOI: 10.1016/j.expneurol.2010.01.017
9. Cota D. CB1 Receptors: Emerging Evidence for Central and Peripheral Mechanisms That Regulate Energy Balance, Metabolism, and Cardiovascular Health. Diabetes/Metabolism Research and Reviews, 2007, vol. 23, pp. 507–517. DOI: 10.1002/dmrr.764
10. Dietrich A., McDaniel W.F. Endocannabinoids and Exercise. British Journal of Sports Medicine, 2004, vol. 38, pp. 536–541. DOI: 10.1136/bjsm.2004.011718
11. El Manira A., Kyriakatos A. The Role of Endocannabinoid Signaling in Motor Control. Physiology, 2010, vol. 25, no. 4, pp. 230–233. DOI: 10.1152/physiol.00007.2010
12. Sparling P.B., Giuffrida A., Piomelli D. et al. Exercise Activates the Endocannabinoid System. NeuroReport, 2003, vol. 14, no. 17, pp. 2209–2211. DOI: 10.1097/00001756-200312020-00015
13. Antunes H.K., Leite G.S., Lee K.S. et al. Exercise Deprivation Increases Negative Mood in Exercise-addicted Subjects and Modifies Their Biochemical Markers. Physiology & Behavior, 2016, vol. 156, pp. 182–190. DOI: 10.1016/j.physbeh.2016.01.028
14. Raichlen D.A., Foster A.D., Seillier A. et al. Exercise-induced Endocannabinoid Signaling is Modulated by Intensity. European Journal of Applied Physiology, 2013, vol. 113, no. 4, pp. 869–875. DOI: 10.1007/s00421-012-2495-5
15. Gleeson M., Walsh N.P., British Association of Sport and Exercise Sciences. The BASES Expert Statement on Exercise, Immunity, and Infection. Journal of Sports Science, 2012, vol. 30, no. 3, pp. 321–324. DOI: 10.1080/02640414.2011.627371
16. Hamedinia M., Sharifi M., Hosseini-Kakhak A. The Effect of Eight Weeks of Aerobic, Anaerobic and Resistance Training on Some Factor of Endocannabinoid System, Serotonin, Beta-Endorphin and BDNF in Young Men. Biosciences Biotechnology Research Asia, 2017, vol. 14, no. 3, pp. 1201–1210. DOI: 10.13005/bbra/2562
17. Lu HC., Mackie K. An Introduction to the Endogenous Cannabinoid System. Biological Psychiatry, 2016, vol. 79, no. 7, pp. 516–525. DOI: 10.1016/j.biopsych.2015.07.028
18. Maccarrone M., Fiori A., Bari M. et al. Regulation by Cannabinoid Receptors of Anandamide Transport Across the Blood-brain Barrier and Through Other Endothelial Cells. Throm-bosis and Haemostasis, 2006, vol. 95, no. 1, pp. 117–127. DOI: 10.1160/TH05-06-0413
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Опубликован
2025-01-10
Как цитировать
Бизяев, В., & Бумарскова, Н. (2025). ВЗАИМОСВЯЗЬ ЭНДОКАННАБИНОИДНОЙ СИСТЕМЫ И ФИЗИЧЕСКОЙ АКТИВНОСТИ. Человек. Спорт. Медицина, 24(S2), 26-30. https://doi.org/10.14529/hsm24s204
Выпуск
Раздел
Физиология
Copyright (c) 2025 Человек. Спорт. Медицина
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