EFFICACY OF VELVET ANTLER SUPPLEMENTS IN PREVENTING THROMBOSIS DURING INTENSE PHYSICAL ACTIVITY

Keywords: velvet antler products, physical activity, hemostasis, microvasculature

Abstract

Aim. This study investigates the protective effects of velvet antler supplements on the hemostatic system and the microcirculatory bed during intense physical activity. Materials and methods. Sixty male Wistar rats were exposed to either 8-hour physical activity alone (control group) or alongside a 30-day pre-treatment regimen of velvet antler products (experimental group). Comparative analyses also included the data obtained from intact animals. Results. The results obtained revealed that velvet antler products significantly mitigated the adverse effects of physical exercise, including thrombocytopenia, enhanced platelet aggregation, and altered fibrinogen levels. Furthermore, it preserved the blood's fibrinolytic and anticoagulant capabilities, normalized microvascular function, and maintained nitric oxide production by endothelial cells. Conclusions. These findings underscore the potential of velvet antler supplements in reducing thrombotic risks associated with intense physical activities, except for microvascular congestion.

Author Biographies

A. Blazhko , Altai State Medical University, Barnaul, Russia

Candidate of Medical Sciences, Associate Professor, Associate Professor of the Department of Normal Physiology, Altai State Medical University, Barnaul, Russia

I. Shakhmatov , Altai State Medical University, Barnaul, Russia

Doctor of Medical Sciences, Professor, Head of the Department of Normal Physiology, Altai State Medical University, Barnaul, Russia.

S. Lisina , Altai State Medical University, Barnaul, Russia

Candidate of Medical Sciences, Associate Professor of the Department of Nor­mal Physiology, Altai State Medical University, Barnaul, Russia.

V. Vdovin , Altai State Medical University, Barnaul, Russia

Candidate of Medical Sciences, Associate Professor, Head of the Department of Pathological Physiology, Altai State Medical University, Barnaul, Russia

L. Obraztsova , Altai State Medical University, Barnaul, Russia

Undergraduate student, Institute of Clinical Medicine, Altai State Medical University, Barnaul, Russia.

References

References on translit

Published
2024-07-25
How to Cite
Blazhko, A., Shakhmatov, I., Lisina, S., Vdovin, V., & Obraztsova, L. (2024). EFFICACY OF VELVET ANTLER SUPPLEMENTS IN PREVENTING THROMBOSIS DURING INTENSE PHYSICAL ACTIVITY. Human. Sport. Medicine, 24(2), 176-182. https://doi.org/10.14529/hsm240222
Section
Sports nutrition