MEDICAL-SOCIAL PROFILE OF PATIENTS WITH ENDOMETRIOSIS

  • E. Igenbaeva South Ural State Medical University, Chelyabinsk, Russian Federation bulba2606@mail.ru
  • T. Uzlova South Ural State Medical University, Chelyabinsk, Russian Federation tatiana.uzlova@mail.ru
  • E. Kurenkov South Ural State Medical University, Chelyabinsk, Russian Federation tatiana.uzlova@mail.ru
Keywords: endometriosis, medical-social profile, childbearing age

Abstract

Aim. To study the medical-social profile of patients with endometriosis. Materials and Methods. Life-history based study included 97 women who had undergone laparoscopic surgery and had histologically confirmed endometriosis for the period from May 2015 till March 2016. Among them 21.5% had small endometriosis lesions, 54.5% – cystic ovarian endometriosis, 8.5% – retrocervical endometriosis, and 15.5% – adenomyosis. Results. Mean age of the investigated group was 32 ± 6.7. Minimum and maximum values were 18 and 45, respectively. According to occupational history, 74.5% of patients were engaged in the intellectual work, 6% – in physical work, 16.5% were unemployed, and 3% were students. The majority of patients were city-dwellers. Somatic pathology assessment revealed that 40.2% of women had chronic gastrointestinal diseases (gastritis, colitis, cholecystitis). 9.3% of patients suffered from chronic pyelonephritis or chronic cystitis. ENT diseases (chronic tonsillitis, chronic maxillary sinusitis) were observed in 8.9%. The cardiovascular pathology was observed in 6.2% (hypertensive disease). The respiratory disorders were reported by 4.1% of patients (chronic bronchitis, asthma). The analysis of genital system pathology showed that 56.7% of patients had inflammatory diseases of pelvic organs. 64% of women from the investigated group were subjected to STD testing. One in five patients had chlamydiae, ureaplasma, or HPV. Cervical pathology was observed in 37.1% of patients (cervical ectopy, cervicitis). Hyperplastic processes occurred in 17.5% (13.4% – endometrial polyp, 5.2% - cervical canal polyp, 5.2% - endometrial glandular hyperplasia). Uterine myoma was observed in 20.6%. Ovarian tumors were observed in 12.4%. Polycystic ovarian syndrome was observed in 5.2% of women. Conclusion. Study of the medical-social profile of patients with endometriosis has revealed that this disease is most frequently observed in women of childbearing age. External genital endometriosis is likely to prevail in early childbearing age (19–35), meanwhile adenomyosis is more often observed in late childbearing age (36–45). This disease is typical of city-dwelling women engaged in intellectual work. The main symptoms are reproductive disorders (infertility) and pain syndrome affecting the quality of life. Endometriosis is seldom detected by non-invasive diagnostic methods, which means that it is necessary to develop new informative methods in order to confirm the disease.

References

1. Agarkova T.A., Kublinskiy K.S. [Immunologic Risk Factors Reproductive Disorders in Women with External Genital Endometriosis]. Fundamental'nye issledovaniya [Basic Research], 2014, no. 10, pp. 1445–1450. (in Russ.)
2. Adamyan L.V., Kulakov V.I., Andreeva E.N. Endometriozy [Endometriosis]. Moscow, Medicine Publ., 2006. 416 p.
3. Sukhikh G.T., Nazarenko T.A. Besplodnyy brak. Sovremennye podkhody k diagnostike i lecheniyu: rukovodstvo [Barren Marriage. Current Approaches to Diagnosis and Treatment. Manual]. Moscow, GEOTAR Media Publ., 2010. 784 p.
4. Manukhin I.B., Tumilovich L.G., Gevorkyan M.A. Ginekologicheskaya endokrinologiya. Klinicheskie lektsii: rukovodstvo dlya vrachey [Gynecological Endocrinology. Clinical Lectures. A Guide for Physicians]. Moscow, GEOTAR-Media Publ., 2013. 272 p.
5. Damirov M.M., Oleynikova O.N., Mayorova O.V. Genital'nyy endometrioz: vzglyad praktikuyushchego vracha: monografiya [Genital Endometriosis. A View of a Medical Practitioner. A Monograph]. Moscow, BINOM Publ., 2013. 152 p.
6. Detskaya i podrostkovaya ginekologiya: rukovodstvo dlya vrachey [Pediatric and Adolescent Gynecology. A Guide for Physicians]. Moscow, Litterra Publ., 2009. 384 p.
7. Strizhakov A.N., Davydov A.I., Pashkov V.M., Lebedev V.A. Dobrokachestvennye zabolevaniya matki [Benign Uterine Disease]. Moscow, GEOTAR Media Publ., 2014. 312 p.
8. Dubinskaya E.D. [Clinical and Medical History and Genetic Characteristics of Patients with Infertility and Perineal Endometriosis]. Vrach [Doctor], 2014, no. 1, pp. 52–56. (in Russ.)
9. Ishchenko A.I., Kudrina E.A., Stanoevich I.V. [Ishchenko AI Modern Problems of External Genital Endometriosis]. Akusherstvo i ginekologiya [Obstetrics and Gynecology], 2007, no. 5, pp. 67–73. (in Russ.)
10. Dobrokhotova Yu.E. Klinicheskie lektsii po akusherstvu i ginekologii [Clinical Lectures on Obstetrics and Gynecology]. Moscow, GEOTAR Media Publ., 2009. 312 p.
11. Kudrina E.A. [Genital Endometriosis]. Ginekologiya [Gynecology], 2007, no. 3, pp. 37–42. (in Russ.)
12. Linde V.A., Tatarova N.A. Endometriozy. Patogenez, klinicheskaya kartina, diagnostika i lechenie: nauchnoe izdanie [Endometriosis. The Pathogenesis, Clinical Picture, Diagnosis and Treatment. A Scientific Edition]. Moscow, GEOTAR-Media Publ., 2010. 192 p.
13. Alyaeva Yu.G. Narusheniya mocheispuskaniya: rukovodstvo [Violation of Urination. Manual]. Moscow, GEOTAR Media Publ., 2010. 176 p.
14. Popov A.A. [The Role of Immunological Factors in the Development of Different Forms of Endometriosis]. Rossiyskiy vestnik akushera ginekologa [Russian Gazette Obstetrician-Gynecologist], 2014, vol. 14, no. 6, pp. 13–20. (in Russ.)
15. Privalova E.E. [Analysis of Immune Homeostasis in the Development of External Genital Endometriosis in Women with Infertility]. Vestnik Ural'skoy meditsinskoy akademicheskoy nauki [Herald of Ural Medical Academic Science], 2009, no. 2/1, pp. 136–137. (in Russ.)
16. Holoch K.J., Lessey B.A. Endometriosis and Infertility. Clin. Obstet. Gynecol., 2010, vol. 53(2), pp. 429–438. DOI: 10.1097/GRF.0b013e3181db7d71
17. Morassutto C., Monasta L., Ricci G. Incidence and Estimated Prevalence of Endometriosis and Adenomyosis in Northeast Italy. A Data Linkage Study. PLoS One, 2016, Apr 21. (accessed 21.04.2016). DOI: 10.1371/journal.pone.0154227
18. Parazzini F., Esposito G., Tozzi L., Noli S., Bianchi S. Epidemiology of Endometriosis and Its Comorbidities. Eur J Obstet Gynecol Reprod Biol., 2016, Apr 30. (accessed 30.04.2016). DOI: 10.1016/j.ejogrb.2016.04.021
19. Physiol Rev. Physiological Aspects of Female Fertility: Role of the Environment. Modern Lifestyle and Genetics, 2016, no. 96(3), pp. 873–909. DOI: 10.1152/physrev.00023.2015
20. Prescott J., Farland L.V., Tobias D.K. A Prospective Cohort Study of Endometriosis and Subsequent Risk of Infertility. Hum Reprod., 2016, no. 31(7), pp. 1475–1482. DOI: 10.1093/humrep/dew085

References on translit

Published
2016-09-01
How to Cite
Igenbaeva, E., Uzlova, T., & Kurenkov, E. (2016). MEDICAL-SOCIAL PROFILE OF PATIENTS WITH ENDOMETRIOSIS. Human. Sport. Medicine, 16(3), 13-18. https://doi.org/10.14529/hsm160302
Section
Clinical and Experimental Medicine